White Matter Hyperintensity Burden Up for Postmenopausal Women – Consumer Health News

WEDNESDAY, July 6, 2022 (HealthDay News) — Postmenopausal ladies seem to have a better burden of white matter hyperintensity (WMH) than comparable-aged women and men who’re premenopausal, in accordance with a examine revealed on-line June 29 in Neurology.

Valerie Lohner, from the German Center for Neurodegenerative Diseases in Bonn, and colleagues examined the intercourse variations and age dependencies in WMH load throughout the grownup life span in a cross-sectional evaluation involving individuals of the inhabitants-based mostly Rhineland Study (aged 30 to 95 years) who underwent mind magnetic resonance imaging. WMH was quantified utilizing T1-weighted, T2-weighted, and FLAIR photos. Of the three,410 individuals, 1,973 (57.9 p.c) had been ladies, of whom 1,167 (59.1 p.c) had been postmenopausal.

The researchers discovered that the rise in WMH load accelerates with age in a intercourse-dependent method. No distinction was seen in WMH burden for premenopausal men and women of comparable age. However, in contrast with males of comparable age, WMH burden was increased and accelerated sooner amongst postmenopausal ladies. There had been adjustments associated to menopause, with increased WMH for postmenopausal ladies than premenopausal ladies of comparable age. A better WMH burden was seen for ladies with uncontrolled hypertension in contrast with males, which was not associated to menopause standing.

The outcomes of our examine “reveal the need to account for completely different well being trajectories for women and men, and menopausal standing,” a coauthor stated in an announcement. “Our analysis underscores the significance of intercourse-particular drugs and extra attentive remedy for older ladies, particularly these with vascular danger elements.”

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