COVID-19 may increase risk of Alzheimer’s, Parkinson’s, stroke: study

A brand new Danish study discovered COVID-19 outpatients had a better risk of being recognized with Parkinson’s, Alzheimer’s, stroke and bleeding into the mind when put next with COVID-19 damaging sufferers, however most neurological problems weren’t extra frequent after COVID-19 than after different respiratory infections, in keeping with a latest study printed in Frontiers in Neurology this June.  

“More than two years after the onset of the COVID-19 pandemic, the exact nature and evolution of the results of COVID-19 on neurological problems remained uncharacterized,” mentioned lead writer Dr. Pardis Zarifkar, member of the Department of Neurology at Rigshospitalet hospital in Copenhagen, Denmark.  

“Previous research have established an affiliation with neurological syndromes, however till now it’s unknown whether or not COVID-19 also influences the incidence of particular neurological illnesses and whether or not it differs from different respiratory infections.” 

The study, which was not too long ago introduced on the eighth European Academy of Neurology Congress, discovered 43,375 people examined constructive for COVID-19 whereas 876,356 people examined damaging for the illness out of a complete of 919,731 members. 

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The study used electronic health records that covered approximately 50% of Denmark’s population, which has an estimated population of 3 million. 

The study analyzed those who tested positive for COVID-19 and bacterial pneumonia in hospital-based facilities between February 2020 and November 2021, as well as reviewed influenza patients from the corresponding pre-pandemic period between February 2018 and November 2019. 

Out of the 43,375 patients who tested positive for COVID-19, 35,362 were outpatients while 8,013 were hospitalized.  

The researchers found the outpatients who tested positive for COVID-19 had a 3.5 times the risk of being diagnosed with Alzheimer’s illness, 2.6 occasions elevated risk with Parkinson’s illness, 2.7 occasions elevated risk with ischemic stroke and 4.8 occasions elevated risk with intracerebral hemorrhage, which is bleeding within the mind.  

But when the researchers in contrast the relative risk of neurological disorders with different respiratory diseases, equivalent to influenza, the elevated risk of most neurological illnesses was not increased in COVID-19-positive sufferers in comparison with these recognized with different respiratory diseases – with one exception.  

Brain illness prognosis with medical physician seeing Magnetic Resonance Imaging (MRI) movie diagnosing aged ageing affected person neurodegenerative sickness drawback for neurological medical remedy. But when the researchers in contrast the relative risk of neurological problems with different respiratory diseases, equivalent to influenza, the elevated risk of most neurological illnesses was not increased in COVID-19-positive sufferers in comparison with these recognized with different respiratory diseases — with one exception.  
(iStock)

The researchers discovered the risk for ischemic stroke elevated amongst COVID-19 hospitalized sufferers when in comparison with inpatients with influenza. 

The study was restricted as a result of it didn’t account for potential confounding variables like socioeconomic, life-style, pre-existing comorbidities and size of hospitalization. 

Medical illustration of a mind with stroke signs. The researchers discovered the risk for ischemic stroke elevated amongst COVID-19 hospitalized sufferers when in comparison with inpatients with influenza. 
(iStock)

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Although the study included a big inhabitants, it was solely in a position to overview a subset of the nation’s absolute quantity of examined people as solely COVID-19 assessments carried out within the hospital amenities are registered within the Danish digital well being report system that the study used to research the information. 

“While the risk of ischemic stroke was elevated with COVID-19 in comparison with influenza, reassuringly, most neurological problems don’t look like extra frequent after COVID-19 than after influenza or community-acquired bacterial pneumonia,” the researchers concluded.  

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“Frequencies of a number of sclerosis, myasthenia gravis, Guillain-Barré syndrome and narcolepsy didn’t differ after COVID-19, influenza and bacterial pneumonia,” the study added.  

“These findings will assist to tell our understanding of the long-term impact of COVID-19 on the physique and the function that infections play in neurodegenerative illnesses and stroke,” Zarifkar mentioned.